Avicel Microcrystalline cellulose is composed of insoluble fibre and does not contribute any other material of nutritional importance. It is a white, free-flowing powder. This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication. cas:9032-51-3 msds CELLULOSE PAB. There may be more fiber in your food than you realized. It . <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 6 0 R/Group<>/Tabs/S>> SUBSTANCE IDENTIFICATION 1.1. endobj It can be processed both via wet granulation and direct compression, as well as roller compression and extrusion-spheronisation. GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA 1. The wood pulp is depolymerized by acid hydrolysis and turned from a fibrous material to a white freely-flowing powder. : 160182. Avicel PC 611 Microcrystalline Cellulose. Generally, these can be classified into two broad groups: Standard grades, and Co-processed grades. The most. Quantity: 1 700 kgs. They are made up of sulfated and non-sulfated repeating units of galactose and 3,6-anhydrogalactose. Magazine: Material safety data sheet - FMC Corporation. Material Safety Data Sheet Ethyl Alcohol 70 ACC 91791 April 21st, 2019 - Material Safety Data Sheet Ethyl Alcohol 70 ACC 91791 Section 1 Chemical Product and Company Identification Ethanol has been shown to produce fetotoxicity in the embry o or fetus of laboratory animals Prenatal Chemical waste generators must determine stream In many applications, one METHOCEL product can perform the job of two, three or even more ingredients saving money and time. Avicel co-processed grades are co-spray dried blends of Avicel microcrystalline cellulose with synergistic pharmaceutical excipients to yield functional benefits beyond simple physical blends. Avicel Microcrystalline Cellulose: A Guide to Grades and Uses, Working Hours (Mon to Friday): 08:30 - 17:30, legendary Canadian-born chemist, Orlando Aloysius Battista, United States Pharmacopoeia and National Formulary, United States Food and Drug Administration, Quantitative nutritional analysis of Avicel Microcrystalline cellulose (in 100g), https://doi.org/10.1016/0378-5173(95)04231-8, https://doi.org/10.1016/j.ejpb.2004.05.009, https://doi.org/10.1002/9783527682935.ch04, Pharmaceutical Acronyms and Abbreviations, Glossary of Terms Used in the Pharmaceutical Industry, Standard Terms & Conditions Of Sale Of Goods And Services, 4-O-[(1S)-hexopyranosyl]-D-glycero-hexopyranose. Learn about our new global sustainability platform, Learn about FMC's industry leading goal of net-zero emissions by 2035, Learn about FMC's differentiated biologically-based crop solutions. Material Safety Data Sheet or SDS for Cellulose microcrystalline 102331 from Merck for download or viewing in the browser. Explore how we work and why we apply science and creativity for a better world to everything we do. common form is used in vitamin supplements or tablets. Microcrystalline cellulose is a commonly used excipient in the . In Cellulose and Cellulose Derivatives in the Food Industry, T. Wstenberg (Ed. 8 0 obj /Contents 4 0 R stream Aqueous suspensions of microcrystalline cellulose have . ( Avicel PH-101. : 9004-34-6 Date Approved: 01/31/2008 . CAS 9004-34-6, pH 5 - 7.5. };khd5x=fr 1. Validity Area. By utilizing proprietary co-processing technologies, Dupont also manufactures LATTICE NTC products. FMC, JRS and Mingtai were estimated to hold for . q9;v80q>jZ However, if handling bulk powders, observance of appropriate safeguards is recommended. Material Safety Data Sheet or SDS for Microcrystalline cellulose 9004-34-6 from chemicalbook for download or viewing in the browser. >> A family of polysaccharide products that allow distinctive drug delivery solutions. The short-term limit for total inhalable dust is 20 mg/m3. LATTICE Microcrystalline Cellulose by Dupont, is an alpha cellulose obtained from naturally ocurring cellulose found in wood pulp, which is an equal structuring polysacharide that is found on fruits and vegetables. %PDF-1.3 More sophisticated drug discovery techniques have led to pipeline compounds that require solubility enhancement to be therapeutically effective. /PRNewswire/ -- ReportsnReports added Global Microcrystalline Cellulose (MCC) Market Growth 2019-2024 to its online research database. LATTICE Microcrystalline Cellulose has many important uses within the food, pharma, specialty applications and industrial such as non-stick coatings, insulation of wiring, crop protection and paints,coats and inks. MATERIAL SAFETY DATA SHEET Product Name: MICROCRYSTALLINE CELLULOSE Date/ Revised: 27/November/2012 Page 4 of 4 15. EMCOCEL XLM 90. 4 0 obj It is highly versatile and is therefore also widely used in topicals and semi-solid & liquid dosage forms, including ointments, creams, gels, pastes, solutions, suspensions, and emulsions. It is widely used within the pharmaceutical, food, and cosmetic sectors as a formulation aid. Cellulose, microcrystalline | C14H26O11 | CID 14055602 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . Fiber supplements can lessen the absorption of some . ]2}Sb2Wdn-;^}n(/;r\'l3--l~ kuI?H>$7;!l|g|i4&dtb/O3!C!#\qpg+>Q0OM It is . Accumulation of overhead settled dust may form explosive concentrations in air when disturbed and dispersed. %PDF-1.5 Fmc Corporation: Ultra-fine microcrystalline cellulose compositions and process . Patel, F. Podczeck, Investigation of the effect of type and source of Microcrystalline Cellulose on capsule filling, International Journal of Pharmaceutics, 128 (1996) 123-127. It is available in different grades and particle sizes. These, in turn, are assembled into fibrils in the cell wall. ( Researcher's newest research report, the "Wood Pulp Based Microcrystalline Cellulose Industry Forecast" looks at past sales and reviews total world Wood Pulp Based Microcrystalline Cellulose sales in 2022, providing a comprehensive analysis by region and market sector of . l~5C %&'()*456789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz The MCC can be synthesized by different processes such as reactive extrusion, enzyme mediated, steam explosion, and acid hydrolysis. MATERIAL SAFETY DATA SHEET Avicel PC 611 Microcrystalline Cellulose Page 1 of 8 MSDS Ref. There have always been two different points of view for the liquidity of MCC. Regulatory Information << Upon ingestion, microcrystalline cellulose is not absorbed into the blood stream and therefore has little toxicological potential. Eur., JPE . The smallest units, the elementary fibrils (cellulose crystalline strands) are made up of many -(1-4) glucose chains which are bundled to form microfibrils. Same quality to grades 102/90M, but very low moisture content (< 1.5 %) for processing water-sensitive actives. Studies from the World Health Organisation and the European Food Safety Agency have concluded that Microcrystalline cellulose has no safety concerns for the public when used in animal nutrition. Avicel Microcrystalline cellulose is available in many grades, which differ in particle size, bulk density, and moisture content. w !1AQaq"2B #3Rbr X]s ;/4'OslUK:|QY`IL|w @ I!*2T~IN?*}y2*49]yOQ*VG%Gu,;&9zE{q==xvrv}rd(yG*qN6E0K$IBWhe : CL-611NF Date Approved: 01/13/2010. Assay for carboxymethycellulose sodium, wt % 8.3 to 13.8 . %PDF-1.4 : 160182 Date Approved: 05/25/2010 Revision No. Microcrystalline cellulose 9004-34-6 <1 Synonyms are provided in Section 1. } !1AQa"q2#BR$3br The global microcrystalline cellulose (MCC) market was valued at $401.1 million in 2021, and is projected to reach $712.9 million by 2031, growing at a CAGR of 5.9% from 2022 to 2031. 2021 Annual Report. /Type/Page . JRS Pharma: PROSOLV SMCC 90: Microcrystalline Cellulose, Colloidal Silicon Dioxide: 125: 0.25 - 0.37: Formulas in which a balance of flow and compaction is required. The chemical structure of cellulose is shown below: In the biosynthesis of cellulose, two molecules of -D-glucose molecules combine via a condensation reaction (elimination of one molecule of water) to form the so-called cellobiose unit. A schematic illustration of the manufacturing process for Avicel Microcrystalline cellulose is shown below. The figure below illustrates the structural organisation of cellulose within plants. }o]X4]. TEXTURECEL NaCMC is applied in oral solids, such as granules and pellets, powders as well as coatings for tablets. cas:9000-11-7 msds Carboxymethyl cellulose. All Rights Reserved. The polymers added organosolubility further creates advantages for employing HPMC in solvent spray-drying applications. xv}O2' H~KEe9>G/,:9\i /Producer(Sub Systems, Inc.)/CreationDate(D:20181207095625+05'00')/ModDate(D:20181207095625+05'00')/Creator(Sub Systems, Inc.) Co-processed excipients deliver functional synergies to address formulation challenges with simplified, single ingredient solutions. Microcrystalline Cellulose (MCC) Manufacturing Industry. In roller compaction, Avicel Microcrystalline cellulose improves compaction during the ribbon phase, enabling a trouble-free process while also preserving the plasticity of the compacts. Microcrystalline cellulose is produced by subjecting to a high shear treatment, at elevated temperature and pressure, a reaction mixture of a cellulose material, an active oxygen compound and water, for a time effective to depolymerize the cellulose material. Although the breakup of cellulose to form colloidal microcrystalline cellulose has no impact on calorific content of the material, colloidal microcrystalline cellulose contain soluble components (hydrocolloids) that are introduced during processing, which add calories to the product. Description: Microcrystalline Cellulose is a term for refined wood pulp manufactured through plant fibre hydrolysis. J]3yzZ2Z$mZ7o%-Xyq'()V9KX0gk~AA Cu:3(]N"AQdUt~h|P iq/iVO"5VI}dn.#q^(fJ),BN yb5*4reh1"!E?mR*%fK,e4?A\{OAXr1' tx&Ul{J,57n%PV E2eMS5'UOL wdD{s)4N-m ab K * ~CVHg}{J2.M}O)^}|Z{V+ >AW|? eqgP}OF'v7heLP&Y,eoo`x7lR}0iRVP],=`_2rS'*X$b)+XV2;fbQDgkgx:IZ|v>lDD/TDqz %RL FMC Corporation 2929 Walnut Street Philadelphia, PA 19104 (215) 299-6000 (General Information) . Combinations of microcrystalline cellulose (MCC) and sodium carboxymethyl cellulose (Na-CMC) are commonly used as stabilising agents and suspending agents in pharmaceutical formulations. The United States Food and Drug Administration considers microcrystalline cellulose a safe material for all animal species. Chemsrc provides Cellulose microcrystalline(CAS#:9004-34-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. For this reason, nutritionists regard standard powdered microcrystalline cellulose as having zero energy content. Have an order or account question, find answers in our Online Support articles. SUBSTANCE IDENTIFICATION 1.1. Interestingly, the discovery of Avicel was accidental, the team was attempting to break up hydrolysed cellulose using a Waring Blender. cas:9004-36-8 msds CELLULOSE ACETATE BUTYRATE. ( Manufacturer: FMC BioPolymer. Apply today! AFFINISOL HPMC HME offers hot melt extrusion process flexibility in choosing a polymer viscosity that optimizes drug release profiles and against the factors affecting solubility. As one of the most robust and efficient excipients, it tolerates high salt content, high temperature and is stable in a wide pH range. Dyvo5bp#bR W7~IF C" d6zLz~!#>@HO}sx;hm>> : 9 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication . Avicel co-processed products are high functionality excipients offering improved powder flow, granule properties, tablet compression, and mouth feel. <> HMo@9, U Q!R/1*;` <> Aquacoat sustained release coating is a pseudo latex aqueous dispersion of water insoluble polymers used for sustained and enteric coating applications. Solid dispersions are one of the key technologies for formulating oral solid dosage forms containing APIs with bioavailability challenges. Learn about FMC's industry leading goal of net-zero emissions by 2035. 4 0 obj The current product range and recommended usage are summarised below: Microcrystalline Cellulose is currently listed in the United States Pharmacopoeia and National Formulary, the European Pharmacopeia, the Japanese Pharmacopoeia, the British Pharmacopoeia, in addition to the Indian and Chinese Pharmacopeia, to name but a few. CAS #: 9004-34-6 1.6. METHOCEL products have been in continuous production for more than 70 years with production facilities and deep product expertise located around the globe. Microcrystalline Cellulose Side Effects. ]c\RbKSTQ C''Q6.6QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ p@" CAS #: 9004-34-6 . Microcrystalline cellulose has excellent compressibility properties and is widely used in solid forms such as tablets that are hard, but can dissolve quickly, and this has increased its demand in . Synergies to simplify formulation challenges and reduce operational costs. MCC helps in the formation of spheres because of its . INCI. Quick Links. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product identifiers Product name : Avicel PH-101 Product Number : 11365 Brand : Fluka CAS-No. 10.1 Future Forecast of the Global Microcrystalline Cellulose Market from 2023-2028 Segment by Region 10.2 Global Microcrystalline Cellulose Production and Growth Rate Forecast by Type (2023-2028 . ETHOCEL premium ethylcellulose resins are water-insoluble polymers. A., and Smith, P. A. G2W4de=u183KGH{ vQ#4:1\wc These include amphiphilicity, a higher degree of crystallinity, surface area, higher hydration properties, and morphology. Ac-Di-Sol Croscarmellose Sodium is one of our flagship offerings for pharmaceutical manufacturers. Alginates from IFF are an excellent choice for consistent performance in a variety of applications. BIOACCUMULATIVE POTENTIAL (AEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEM %)piQpFNnFu\4m4( ESE;m& %QL((((((((((((((((((((((((((((((((((((((((P3NhC Low use levels of GRINDSTED Xanthan Gum are sufficient to provide desired viscosities and textures. Test Data Available. The highly reactive amorphous regions selectively hydrolyze, releasing the crystallites, which are subsequently mechanically dispersed. Report Category. It is also inert and biocompatible. : 5 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication Standard, 29 CFR 1910.1200 and Canadas Workplace Hazardous Materials Information System (WHMIS) requirements. PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME: Avicel PC 611 Microcrystalline Cellulose CHEMICAL FAMILY: Carbohydrate, Cellulose Derivative SYNONYMS: Microcrystalline cellulose (INCI name): MCC, cellulose gel; Sodium Carboxymethylcellulose: NaCMC, CMC, SCMC, Carboxymethylcellulose GENERAL USE: Personal Care MANUFACTURER FMC BioPolymer 1735 Market Street Philadelphia, PA 19103 (800) 526-3649 (General Information) msdsinfo@fmc.com (Email - General Information) FMC Europe NV Avenue Mounier 83 1200 Brussels, Belgium 353 21 435 4133 (General Information - Cork, Ireland) 2. Avicel PC 611 (FMC Biopolymer) Supplied by. MSDS Ref. Similarly, the European Food Safety Agency has also evaluated Microcrystalline cellulose and established that it is not absorbed systemically and excreted unchanged. The charts below provide guidance on how to select and use standard and co-processed grades of Avicel Microcrystalline cellulose in pharmaceutical products. 1 0 obj It should be noted that native cellulose itself is completely indigestible, and its hydrolysis during the production of microcrystalline cellulose does not alter its behaviour in the intestine. We are the leading manufacturer of Microcrystalline Cellulose coated with - RC 581 Grade in the industry. Delivering efficient and robust formulations. Avicel RC-591 & CL-611 - Description. The range of products includes three basic types of carrageenan kappa, iota and lambda from various species of red seaweed. % More than 65 years later, Avicel continues to command global acceptance, with no signs of its popularity waning. endobj % 130. Avicel Microcrystalline cellulose is manufactured in the United States of America by Dupont. 1.3. *r_ *?~4$ &0Y# : 1. ;(Imu9Jv_ YhnHTbwP*:mg"T{BO;!QR e,cqO! The table below lists the typical nutritional information of microcrystalline cellulose: Quantitative nutritional analysis of Avicel Microcrystalline cellulose (in 100g)1. Trademarks: Avicel PH-102. Powder becomes slippery when wet. <> F. Steele, M. Tobyn, S. Edge, A. Chen & J. N. Staniforth.Physicochemical and Mechanical Evaluation of a Novel High Density Grade of Silicified Microcrystalline Cellulose, Drug Development and Industrial Pharmacy, 30:1 (2004), 103-109. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING Material Name: Estradiol Tablets Trade Name: RONFASE . 102331. /MediaBox [0 0 612 792] In 1964 FMC, Corporation . ChemicalBook. The fumarate moiety of Alubra increases its melting temperature, which allows for greater functionality at high press speeds while the stearate chain maintains the lubricity of the compound and supports low ejection forces. Microcrystalline cellulose was negative in the Ames mutagenicity assay [FMC Study Number I91-1189], and caused no Avicel PC 611 (FMC Biopolymer) . Avicel Microcrystalline cellulose was discovered in 1955 by a team at FMC Corporation, led by the legendary Canadian-born chemist, Orlando Aloysius Battista, which he initially named 'mechanically disintegrated D.P cellulose. /Resources 2 0 R Pharmacel 112 is a directly compressible microcrystalline cellulose grade with a low moisture content (LOD Max. Avicel Microcrystalline cellulose was discovered in 1955 by a team at FMC Corporation, led by the legendary Canadian-born chemist, Orlando Aloysius Battista, which he initially named mechanically disintegrated D.P cellulose. Material safety data sheet - FMC Corporation. PDF (2.77 mb) 2021 FMC Sustainability Report. From anti-reflux to biomedical implants, alginates are uniquely suited for a wide range of applications. Microcrystalline cellulose in certain fiber supplements may cause mild side effects ().These may include gas, bloating and increased stool production.. Explore how you can develop your career and bring your creative ideas to life at IFF. We are artists at heart and creators by nature. We respect your privacy FMC Privacy Policy. Buy Chemicals. 3 0 obj Burger King, McDonald's and other fast food companies list in the ingredients of several of their foods, microcrystalline cellulose (MCC . The cellulose molecule is formed through repeated condensation of cellobiose units. Truly distinctive drug delivery solutions. Microcrystalline cellulose (MCC) is a pure partially depolymerized cellulose synthesized from -cellulose precursor (type I), obtained as a pulp from fibrous plant material, with mineral acids using hydrochloric acid to reduce the degree of polymerization. Terms and Conditions Compliance Solutions Industries About 3E News & Events . All rights reserved. Product Name: MICROCRYSTALLINE CELLULOSE Date/ Revised: 27/November/2012 Page 1 of 4 1. To help, weve put together a simple guide for selecting Avicel Microcrystalline cellulose grades, with simple explanations of some of the most common grades, plus recommendations that will serve the majority of buyers. Microcrystalline cellulose -The oldest polymer finds new industrial uses,. No. \C[i+rY2$V,,WT#_)3K?=/fW%[,lE"V?C PipEAz_xO;`cZsC0qcx;@tp]c*T7ge @Mty?]@SNmpf/]q#I,G1I?SR.@z*Xb KjR hb{T$CQrr Yx%O@~57eL5S\r-|EZ)Y.C]KuIlW]@12KY,S]C"e%b*|YX122igjl; @! ,}b;XQ})+l{~d_=sUtl V"CbKas+;fc>]bt#F,Md]]!5xae ;}rr^NI]rUc^,5Lc(fyyp*a=~U}WveuTLYX/ _V{#* g(*Rrm0gyv9i@0UT:A+{eW/y BS3_!Qv rt^BN! Enter your [postal] code to see information about local products, representatives and retailers, along with special offers in your area. Eur., JP Product Specifications: Chemical and Physical: Loss on drying 2.0 - 5.0 %* Bulk density 0.29 - 0.36 g/cc Identification A, B Passes Degree of polymerization NMT 350 units pH 5.5 - 7.0* Conductivity NMT 75 S/cm (Microcrystalline Cellulose Market Pr. Browse Avicel PH-101 and related products at MilliporeSigma. CoA. CAS #: 9004-34-6 However, consumption of large quantities of the material may have a laxative effect. Page 1 of 8. Synonyms: Cellulose, Cellulose powder, Cotton linters. << Micro Crystalline Cellulose. The table below lists the most important chemical identifiers applicable to Avicel Microcrystalline cellulose. MATERIAL SAFETY DATA SHEET Avicel RC/CL Microcrystalline Cellulose and Sodium Carboxymethylcellulose MSDS Ref. Cellulose microcrystalline MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. To overcome the pitfalls of known overlays, we tested suspensions of microcrystalline cellulose Avicel RC/CLtrade mark as overlay media in the plaque and plaque-inhibition assay of influenza viruses. 4 0 obj These grades have particle sizes ranging from <30 to approximately 200. on Avicel microcrystalline cellulose, the most trusted excipient brand for decades. Product and Company Identification . {ddn(Y?I#K-}t|l #:FHF'D)/)"{k\pM @LRvdSbi#$yg+\0-U VE-2CZ*K&V.MiLeu86)23NI+6tkLSfmWuR.T\>;8]$ipHJ_)*P.FHyD R^PQ4EC l 4h+:6:]=3?B}Y#eAs(l)V6IOG,OM4'R3#^Op?gYZ; m#6@6O$ ;Ro|U$NSs*\neT &CcB7ysrg7;6Eax $R9+q,)}YK-0/SI0K}d WQC}>e|Gs_Q'+mB| X{URv/Z'` 4w'8sC~ cON&pIk:F/Q&u~.S{"% pg:lfx -. Avicel PH-200 microcrystalline cellulose NF, Ph. It works as a moisture sponge and permits the controlled growth of spheroids. stream Cellulose microcrystalline Revision Date 25-Dec-2021 SARA 313 Not applicable SARA 311/312 Hazard CategoriesSee section 2 for more information CWA (Clean Water Act) Not applicable Clean Air Act Not applicable OSHA - Occupational Safety and Health Administration Not applicable CERCLA Not applicable California Proposition 65 This product contains the following Proposition 65 chemicals. Various Gelcarin and Viscarin carrageenan grades are used by the pharmaceutical industry to achieve specific gelling for controlled drug release, thickening, and stabilizing properties desired in various formulations. F. Lerk, G.K. Bolhuis, A.H. De Boer, Effect of Microcrystalline Cellulose on liquid penetration in and disintegration of directly compressed tablets, Journal of Pharmaceutical Sciences, 68 (1979) 205-211. However, with many different grades (standard and specialty) on offer, how do you select the correct material for your needs? PDF (4.11 mb) Footer menu 1. This Microcrystalline Cellulose . An internally cross-linked sodium carboxymethyl cellulose (NaCMC), it aids in the disintegration and drug dissolution of pharmaceutical tablets, capsules, and granules. Safety Data Sheet (SDS) Viewer. Protect them from sunshine or rain. endobj Unique functionality for a broad range of pharmaceutical applications. Microcrystalline cellulose (Avicel, FMC Corporation) is prepared by acid hydrolysis of cellulose using 2 M hydrochloric acid at 105 C for 15 min. EINECS #: 232-674-9 1.7. It is made from purified partially depolymerised Alfa cellulose relatively free from both organic and inorganic contaminants. Wu, K. Zuurman, H.W. Formulators select it when they need to enhance a formulations robustness especially when less compactable diluents and binders are used. It is hygroscopic and insoluble in water. 1.3. FMC Corporation: Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations DE102009022738A1 (de) * 2009-05-26: 2010-12-09: J. Rettenmaier & Shne Gmbh + Co. Kg . Ac-Di-Sol Croscarmellose Sodium is one of our flagship offerings for pharmaceutical manufacturers. JFIF ` ` ZExif MM * J Q Q Q C 86dXeaAjHe%d*`&>>&_p}=X|_% fTtC aB s!YaxHWtGr"GQ 5S"fMS+_;x@@5 zjrK=;OA:il)b> e ei'wm~oh!=Z@Y:J0#8On`T./iC}^o%7KS"$ rf*Z;JTL-uOHH%%Z,029J_ ( endstream endobj 526 0 obj 465 endobj 527 0 obj << /Filter /FlateDecode /Length 526 0 R >> stream
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